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Claudine Kraft

Claudine Kraft
Kraft, Claudine
Prof. Dr. rer. nat,
Institute for Biochemistry and Molecular Biology, University of Freiburg
Stefan-Meier-Str. 17, D-79104 Freiburg
claudine.kraft[a]biochemie.uni-freiburg.de
 
Current position
Full Professor (W3) of Biochemistry, Institute for Biochemistry and Molecular Biology

 

 

 

 

Research topic in GRK 2606: Autophagy initiation

University training and degree(s)
2000 – 2001     Diploma thesis in the group of Prof.   Stephen High, University of Manchester, UK
1997 − 2001     University of Basel, Switzerland, Diploma program in Molecular Biology, Diploma in “Biology II”
 
Advanced academic qualifications
2015                 Habilitation “Venia legendi”, in Molecular Biology, University of Vienna, Austria
2005                 Dr. rer. nat.; PhD thesis in the group of Dr. J.M. Peters, Research Institute of Molecular
                         Pathology (IMP), Vienna, Austria (Assistant Professorship, tenure-track)
                       
Postgraduate professional career
Since 2017       Full Professor (W3) at the Institute of Biochemistry and Molecular Biology,
                         University of Freiburg, Germany
2015 – 2017     Associate Professor (tenured), University of Vienna, Austria
2011 – 2014     Junior group leader at the Max F. Perutz Laboratories (MFPL), University of Vienna, Austria
2006 – 2011      Postdoctoral research in the group of Prof. Matthias Peter, Institute of Biochemistry,
                          ETH Zürich, Switzerland
Other
2018                  ERC Consolidator grant
2017                  FWF START Award
2017                  Advisory Editorial Board of Life Science Alliance
2014                  EMBO Young Investigator Award
2012                  Academia Net member
2011                  WWTF Starting grant
2008                  Swiss National Foundation MHV postdoc fellowship
2006                  EMBO long-term fellowship
2005                  PhD Award of the Campus Vienna Biocenter

 

10 important publications

  1. Bas, L., Papinski, D., Licheva, M., Torggler, R., Rohringer, S., Schuschnig, M., Kraft, C. (2018). Reconstitution reveals Ykt6 as the autophagosomal SNARE in autophagosome-vacuole fusion. J. Cell Biol. 217, 3656-3669. DOI: 10.1083/jcb.201804028
  2. Torggler, R., Papinski, D., Brach, T., Bas, L., Schuschnig, M., Pfaffenwimmer, T., Rohringer, S., Matzhold, T., Schweida, D., Brezovich, A., Kraft, C. (2016). Two Independent Pathways within Selective Autophagy Converge to Activate Atg1 Kinase at the Vacuole. Mol. Cell 64, 221-235.
  3. Rebsamen, M., Pochini, L., Stasyk, T., Araujo, M., Galluccio, M., Kandasamy, R., Snijder, B., Fauster, A., Fudashevskaya, E., Bruckner, M., Scorzoni, S., Filipek, P., Huber, K., Bigenzahn, J., Heinz, L., Kraft, C., Bennett, K., Indiveri, C., Huber, L., Superti-Furga, G. (2015). SLC is an integral component of the lysosomal amino acid-sensing machinery that controls mTORC1 activity. Nature 519, 477-481.
  4. Pfaffenwimmer, T., Reiter, W., Brach, T., Nogellova, V., Papinski, D., Schuschnig, M., Abert, C., Ammerer, G., Martens, S., Kraft, C. (2014). The Hrr25 kinase promotes selective autophagy by phosphorylating the cargo-receptor Atg19. EMBO Rep. 15, 862-870.
  5. Papinski, D., Schuschnig, M., Reiter, W., Wilhelm, L., Barnes, C., Majolica, A., Hansmann, I., Pfaffenwimmer, T., Kijanska, M., Stoffel, I., Lee, S.S., Brezovich, A., Lou, H.J., Turk, B.E., Aebersold, R., Ammerer, G., Peter, M., Kraft, C. (2014). Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase. Mol. Cell 53, 471-483.
  6. Kraft, C.*, Kijanska, M., Kalie, E., Siergiejuk, E., Lee, S., Semplicio, G., Stoffel, I., Brezovich, A., Verma, M., Hansmann, I., Ammerer, G., Hofmann, K., Tooze, S., Peter, M.* (2012). Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy. EMBO J. 31, 3691-3703. *corresponding
  7. Romanov, J., Walczak, M., Ibiricu, I., Schüchner, S., Ogris, E., Kraft, C., Martens, S. (2012). Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation. EMBO J. 31, 4304-4317.
  8. Kraft, C., Peter, M., Hofmann, K. (2010). Selective autophagy: ubiquitin-mediated recognition and beyond. Nat. Cell Biol. 12, 836-841 (review).
  9. Bodenmiller, B., Wanka, S., Kraft, C., Urban, J., Campbell, D., Pedrioli, P.G., Gerrits, B., Picotti, P., Lam, H., Vitek, O., Brusniak, M.Y., Roschitzki, B., Zhang, C., Shokat, K.M., Schlapbach, R., Colman-Lerner, A., Nolan, G.P., Nesvizhskii, A.I., Peter, M., Loewith, R., von Mering, C., and Aebersold, R. (2010). Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast. Sci. Signal. 3, rs4.
  10. Kraft, C.*, Deplazes, A., Sohrmann, M., Peter, M.* (2008). Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease. Nat. Cell Biol. 10, 602-610. *corresponding