Ulrich Maurer

Maurer, Ulrich

PD Dr. phil.nat,
Institute of Molecular Medicine and Cell Research, University of Freiburg
Stefan-Meier-Str. 17, D-79104 Freiburg
ulrich.maurer[a]mol-med.uni-freiburg.de

Current position

Research group leader, Institute of Molecular Medicine and Cell Research

Research topic in GRK 2606: Proteases in cell survival

University training and degree(s)

1988 − 1994 Studies in Biotechnology in Bingen, Germany (Dipl.-Ing. Biotechnologie (FH))

Advanced academic qualifications

1994 − 1999 PhD in Biochemistry, University of Frankfurt/Main

2017 Habilitation in Experimental Medicine

Postgraduate professional career

since 2006 Independent research group leader, Institute for Molecular Medicine and Cell

Research, University of Freiburg, Germany

2000 − 2005 Postdoctoral fellow in the group of Dr. Douglas Green, La Jolla Institute

for Allergy and Immunology, San Diego, USA

1999 − 2000 Postdoctoral fellow, University of Ulm

Other

since 2018 Editorial Board member Cell Death and Disease

since 2011 Associate Member, Centre for Biological Signalling Studies BIOSS

since 2011 Principal Investigator, Spemann Graduate School of Biology and Medicine

10 important publications

Schubert, F., Rapp, J., Brauns-Schubert, P., Schlicher, L., Stock, K., Wissler, M., Weiss, M., Charvet, C., Borner, C., Maurer, U. (2018). Requirement of GSK-3 for PUMA induction upon loss of pro-survival PI3K signaling. Cell Death Dis. 9, 470ff
Brauns-Schubert, P., Schubert, F., Wissler, M., Weiss, M., Schlicher, L., Bessler, S., Safavi, M., Miething, C., Borner, C., Brummer, T., Maurer, U. (2018). CDK9-mediated phosphorylation controls the interaction of TIP60 with the transcriptional machinery. EMBO Rep. 19, 244-56
Schlicher, L., Wissler, M., Preiss, F., Brauns-Schubert, P., Jakob, C., Dumit, V., Borner, C., Dengjel, J., and, Maurer, U. (2016). SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death. EMBO Rep. 17, 1485-7
Lindner, S.E., Wissler, M., Gründer, A., Aumann, K., Ottina, E., Peintner, L., Borner, C., Charvet, C., Villunger, A., Pahl, H.L., Maurer, U. (2014). Increased leukocyte survival and accelerated onset of lymphoma in absence of MCL-1 S159-phosphorylation.Oncogene33, 5521-4.
Geissler, A., Haun, F., Frank, D.O., Wieland, K., Simon, M.M., Idzko, M., Davis, R.J., Maurer, U., Borner, C. (2013). Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK. Cell Death Differ. 20, 1317-29
Colell, A., Ricci, JE., Tait, S., Milasta, S., Maurer, U., Bouchier-Hayes, L., Fitzgerald, P., Guio-Carrion, A., Waterhouse, NJ., Wei, Li, C., Newmeyer, DD., Beere, HM., Green, D.R. (2007). Glyceraldehyde-3-phosphate dehydrogenase and autophagy protect cells from apoptotic cytochrome c release in the absence of caspase activation. Cell129, 983-997
Viatour, P., Dejardin, E., Warnier, M., Lair, F., Claudio, E., Bureau, F., Marine, JC., Merville, MP., Maurer, U., Green, D., Piette, J., Siebenlist, U., Bours, V., Chariot, A (2004). GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity. Mol. Cell 16, 35-45
Chipuk, J. E., Maurer, U., Green, D. R., Schuler, M. (2003). Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription. Cancer Cell4, 371–381
Charvet, C., Wissler, M., Brauns-Schubert, P., Wang, S.J., Tang, Y., Sigloch, F., Mellert, H., Brandenburg, M., Lindner, S., Breit, B., Green, DR., McMahon, S., Borner, C., Gu, W., Maurer, U. (2011). Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Mol. Cell 42, 584-96
Maurer, U.*, Charvet, C., Wagman, A., Dejardin, E.M., Green, D.R.* (2006). Glycogen Synthase Kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol. Cell 21, 749-60, *co-corresponding authors