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Ulrich Maurer

Maurer, Ulrich
PD Dr. phil.nat,
Institute of Molecular Medicine and Cell Research, University of Freiburg
Stefan-Meier-Str. 17, D-79104 Freiburg
Current position
Research group leader, Institute of Molecular Medicine and Cell Research





Research topic in GRK 2606: Proteases in cell survival

University training and degree(s)
1988 − 1994   Studies in Biotechnology in Bingen, Germany (Dipl.-Ing. Biotechnologie (FH))
Advanced academic qualifications
1994 − 1999   PhD in Biochemistry, University of Frankfurt/Main
2017               Habilitation in Experimental Medicine
Postgraduate professional career
since 2006     Independent research group leader, Institute for Molecular Medicine and Cell
                       Research, University of Freiburg, Germany
2000 − 2005   Postdoctoral fellow in the group of Dr. Douglas Green, La Jolla Institute
                       for Allergy and Immunology, San Diego, USA
1999 − 2000   Postdoctoral fellow, University of Ulm
since 2018      Editorial Board member Cell Death and Disease
since 2011      Associate Member, Centre for Biological Signalling Studies BIOSS
since 2011      Principal Investigator, Spemann Graduate School of Biology and Medicine
10 important publications
  1. Schubert, F., Rapp, J., Brauns-Schubert, P., Schlicher, L., Stock, K., Wissler, M., Weiss, M., Charvet, C., Borner, C., Maurer, U. (2018). Requirement of GSK-3 for PUMA induction upon loss of pro-survival PI3K signaling. Cell Death Dis. 9, 470ff
  2. Brauns-Schubert, P., Schubert, F., Wissler, M., Weiss, M., Schlicher, L., Bessler, S., Safavi, M., Miething, C., Borner, C., Brummer, T., Maurer, U. (2018). CDK9-mediated phosphorylation controls the interaction of TIP60 with the transcriptional machinery. EMBO Rep. 19, 244-56
  3. Schlicher, L., Wissler, M., Preiss, F., Brauns-Schubert, P., Jakob, C., Dumit, V., Borner, C., Dengjel, J., and, Maurer, U. (2016). SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death. EMBO Rep. 17, 1485-7
  4. Lindner, S.E., Wissler, M., Gründer, A., Aumann, K., Ottina, E., Peintner, L., Borner, C., Charvet, C., Villunger, A., Pahl, H.L., Maurer, U. (2014). Increased leukocyte survival and accelerated onset of lymphoma in absence of MCL-1 S159-phosphorylation.Oncogene33, 5521-4.
  5. Geissler, A., Haun, F., Frank, D.O., Wieland, K., Simon, M.M., Idzko, M., Davis, R.J., Maurer, U., Borner, C. (2013). Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK. Cell Death Differ. 20, 1317-29
  6. Colell, A., Ricci, JE., Tait, S., Milasta, S., Maurer, U., Bouchier-Hayes, L., Fitzgerald, P., Guio-Carrion, A., Waterhouse, NJ., Wei, Li, C., Newmeyer, DD., Beere, HM., Green, D.R. (2007). Glyceraldehyde-3-phosphate dehydrogenase and autophagy protect cells from apoptotic cytochrome c release in the absence of caspase activation. Cell129, 983-997
  7. Viatour, P., Dejardin, E., Warnier, M., Lair, F., Claudio, E., Bureau, F., Marine, JC., Merville, MP., Maurer, U., Green, D., Piette, J., Siebenlist, U., Bours, V., Chariot, A (2004). GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity. Mol. Cell 16, 35-45
  8. Chipuk, J. E., Maurer, U., Green, D. R., Schuler, M. (2003). Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription. Cancer Cell4, 371–381
  9. Charvet, C., Wissler, M., Brauns-Schubert, P., Wang, S.J., Tang, Y., Sigloch, F., Mellert, H., Brandenburg, M., Lindner, S., Breit, B., Green, DR., McMahon, S., Borner, C., Gu, W., Maurer, U. (2011). Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Mol. Cell 42, 584-96
  10. Maurer, U.*, Charvet, C., Wagman, A., Dejardin, E.M., Green, D.R.* (2006). Glycogen Synthase Kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol. Cell 21, 749-60, *co-corresponding authors