Riccardo Babic
| Name | Riccardo Babic |
| Education/Training | B. Sc. Biology, M. Sc. Biology, Molecular Biology and Physiology |
| Start of PhD Thesis and Group | 01/2021, Prof. Claudine Kraft |
| Subject of Thesis | Autophagy process in mammals |
| Research Interests | Autophagy, ageing, neurodegenerative diseases, ULK1 complex proteins, mTOR |
| Methods and Techniques | Western Blotting, Co-IP, Crispr/Cas9, PCR, cell culture, microscopy |
| Publications |
Hollenstein DM, Maurer-Granofszky M, Reiter W, Anrather D, Gossenreiter T, Babic R, Hartl N, Kraft C, Hartl M. Chemical Acetylation of Ligands and Two-Step Digestion Protocol for Reducing Codigestion in Affinity Purification-Mass Spectrometry. J Proteome Res. 2023 Sep 15. doi: 10.1021/acs.jproteome.3c00424. Epub ahead of print. Sánchez-Martín P, Kriegenburg F, Alves L, Adam J, Elsaesser J, Babic R, Mancilla H, Licheva M, Tascher G, Münch C, Eimer S, Kraft C. ULK1-mediated phosphorylation regulates the conserved role of YKT6 in autophagy. J Cell Sci. 2023 Feb 1;136(3):jcs260546. doi: 10.1242/jcs.260546. Epub 2023 Feb 9. Eickhorst C*, Babic R*, Rush-Kittle J, Lucya L, Lami Imam F, Sánchez-Martín P, Hollenstein DM, Michaelis J, Münch C, Meisinger C, Slade D, Gámez-Díaz L, Kraft C. FIP200 phosphorylation regulates late steps in mitophagy. J Mol Biol. 2024 May 29:168631. doi: 10.1016/j.jmb.2024.168631. Epub ahead of print. PMID: 38821350. *equal contribution |
|
Licheva, M., Pflaum, J., Babic, R., Mancilla, H., Elsässer J, Boyle E, Hollenstein DM, Jimenez J, Pleyer J, Heinrich M, Wieland FG, Brenneisen J, Eickhorst C, Brenner J, Jiang S, Hartl M, Welsch S, Hunte C, Timmer J, Wilfling F, Kraft C. Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy. Nat Cell Biol (2025). https://doi.org/10.1038/s41556-024-01572-y |
|
|
Licheva, M., Babic, R., Pflaum, J., Mancilla, H., Wilfling, F., & Kraft, C. (2025). To degrade or not to degrade: how phase separation modulates selective autophagy. Autophagy. https://doi.org/10.1080/15548627.2025.2476025 |
|
| Contact | riccardo.babic[at]biochemie.uni-freiburg.de |